Molecular epidemiology of rotavirus in black infants in South Africa.
نویسندگان
چکیده
The molecular epidemiology of rotavirus infections in black infants in Ga-Rankuwa, South Africa, was investigated by polyacrylamide gel electrophoresis. Between 1983 and 1986, 14 different RNA electrophoretic patterns were observed for children with acute gastroenteritis. These electrophoretypes showed a sequential pattern of appearance, with a limited number being present at any one time. In contrast, for neonates only one RNA electrophoretype was detected, which persisted for at least 3 years.
منابع مشابه
Characterization and molecular epidemiology of rotavirus strains recovered in Northern Pretoria, South Africa during 2003-2006.
Rotavirus infection is the most common cause of severe dehydrating gastroenteritis in infants and young children and remains a significant clinical problem worldwide. The severity and the burden of rotavirus disease could be reduced through the implementation of an effective vaccine. The aim of this study was to characterize rotavirus strains circulating in the local community as part of an ong...
متن کاملRotavirus-associated gastroenteritis in black infants in South Africa.
From March 1983 to February 1985, rectal swabs were collected from the black infants admitted to the gastroenteritis unit at Ga-Rankuwa Hospital, Pretoria, Republic of South Africa, to investigate the prevalence of rotavirus-associated gastroenteritis. Overall, 23.1% of the patients tested were found to be positive for rotaviral illness; a definite seasonal pattern emerged, showing a marked inc...
متن کاملRotavirus in South Africa: From discovery to vaccine introduction
Rotavirus was first detected by electron microscopy in young children with diarrhoea in South Africa in 1976, and 25 years later rotavirus vaccine was introduced into the routine childhood immunisation schedule in the country. Prof Barry Schoub played a role in both these events and in many milestones along that journey, from discovery to introduction. Several seminal findings were identified b...
متن کاملAge distribution and seasonal pattern of rotavirus infection in children in Kenya.
The age distribution and seasonal pattern of rotavirus infection were investigated in infants and young children admitted with acute diarrhea at the Kenyatta National Hospital from December 1981 through June 1983. They had acute diarrhea of not more than 10 days duration and had not received antibiotic treatment. Presence of rotavirus in stool was detected by using the WHO enzyme linked immno...
متن کاملPrevalence and diversity of rotavirus strains in children with acute diarrhea from rural communities in the Limpopo Province, South Africa, from 1998 to 2000.
BACKGROUND Data regarding the prevalence and molecular epidemiology of rotavirus infection in rural areas of Africa are limited. In this study the prevalence and genetic diversity of rotaviruses in a rural South African setting were investigated. METHODS During June 1998 to June 2000, 420 stool specimens were collected from children with acute diarrhea who visited primary health care clinics ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 25 12 شماره
صفحات -
تاریخ انتشار 1987